Pigs are one of the closest non-primate species to humans, and have a high level of similarity with humans at both a genetic and physiological level (~95%). The use of pigs as a model for pre-clinical testing could offer substantial benefits, not only by helping to potentially dramatically reduce the level of drug failures in clinical testing, but also in doing so reduce costs and the number of animals that would need to be used for pre-clinical testing. Commercial access to a high quality critical care unit for large animals, in which trails could be contacted, is available through Roslin Technologies.
Large Animal Critical Care unit
The Wellcome Trust Critical Care Laboratory for Large Animals (WT CCLLA) is a high quality unit that offers a means to conduct clinical trials on up to four large animals (e.g. pigs) at a time. It incorporates a surgical unit, critical care beds, recovery and monitoring areas and a CT scanner, and thus offers an ideal facility for running a range of clinical trials in large animal models. It is supported by dedicated and highlight skilled veterinary team, and is managed to Home Office licence standards. Any trails undertaken at the unit can also be supported by a range of diagnostics and pathology capabilities and expertise that are also available through Roslin Technologies. The number of critical care beds will increase to six in 2018 with the opening of a new Large Animal Facility (LARIF) at which is currently under construction. As well as hosting a CT scanner, the LARIF will also house a dedicated MRI scanner which will further increase the level and quality of imaging that can be achieved.
Management of Clinical Trials
Managing of commercial trials using the facility or more generally is also available as a service through Roslin Technologies. Examples of the services available include:
- Clinical trial management/coordination
- Sample management service
- Biobanking service
If you would like more information or would like to discuss a possible project,
please contact us.