Products and Services
Animal iPS Cell Lines
Roslin Technologies are experts in animal cell culture and offer a broad portfolio of services around animal cell technology.
Our inducible pluripotent stem (iPS) cells platform focuses on developing cell lines for cultivated meat technologies, animal cell therapies, gene editing studies, and pharmacological screening and toxicology assays.
These validated iPS cell lines can be differentiated into a range of animal cell types providing broad application.
We offer access to and processing of many animal cell types for clients’ in vitro research activities, as well as working with collaborators and commercial partners to develop in vitro bioassays and therapies.
Genome Editing
Genome editing technology is embedded in several of Roslin Technologies’ platforms.
Through the expertise of our scientists and in partnership with the Roslin Institute and R(D)SVS we have experience in editing:
– Canine cell lines to produce in vitro disease models and develop cell therapies.
– Pig cell lines for industry targets including in the Cultivated Meat sector.
– Aquaculture species through supporting academic research on diseases that challenge the aquaculture industry.
Breeding Programme Services
Roslin Technologies offers bespoke breeding programmes for production enhancement.
These include the delivery of database management, estimated genetic/genomic evaluations for the livestock and aquaculture sectors on a range of production parameters.
We are also developing a customised breeding programme for production of insects as a protein source. Insect protein has commercial application in animal feed and complements our goals to enhance production of livestock and aquaculture. Farming of insects is also a means of bioconversion as insects feed on waste organic matter.
Biobanking
Roslin Technologies offer secure and flexible biobanking services for its clients.
We process and store tissues, cells, blood or DNA at appropriate temperatures to prevent biodegradation. Sample storage periods are flexible depending on your project, from short term to long term. Roslin Technologies uses state-of-the art bar coding systems for sample storage and retrieval logistics.
All systems are monitored 24 hours a day 7 days a week. Backup power supplies, alarms, monitors and emergency systems protect the integrity of your samples. Your samples are security monitored and in secure locked storage. Our standard operating procedures (SOPs) follow good manufacturing practices ensuring uniformity and traceability at all stages. Roslin Technologies offers biobanking at -150°C, -80°C, -20°C and 4°C archiving valuable samples.
Protein Expression Systems & Reagents
We offer protein expression as a service from design of constructs through to delivery of large quantities of high-purity product.
Our platforms have the potential to be used for production of therapeutic proteins, vaccine candidates and research reagents.
Eggcellent Proteins
Research at the Roslin Institute established the technology to create transgenic chickens that produce large quantities of a target protein in their egg-white.
This platform has been commercialised through Roslin Technologies and Porcine CSF1-Fc, Human CSF1-Fc, Canine CSF1-Fc, Human interferon α 2α and Trastuzumab are all available from Eggcellent Proteins.
Monoclonal Antibody Toolbox
A portfolio of monoclonal antibodies has been developed by the Roslin Institute as part of the “Immunological Toolbox” project. Roslin Technologies has agreed an exclusive licence to sell this portfolio of antibodies. Conjugated anti-porcine ADGRE-1, anti-chicken CSF1 and anti-porcine CSF1 are available through Eggcellent Proteins for use in ELISA, flow cytometry and immunohistochemistry studies.
PGC Expression System & Reagents
Our vision is to develop an in vitro expression system via genetic manipulation of chicken primordial germ cells (PGCs). This will provide an intermediate step to identify targets for production of transgenic chickens or to produce smaller quantities of proteins that retain the benefits of chicken-associated post-translational modifications.