In Vitro Research Tools
Protein Expression Systems & Reagents
We offer protein expression as a service from design of constructs through to delivery of large quantities of high-purity product.
Our platforms have the potential to be used for production of therapeutic proteins, vaccine candidates and research reagents.
Research at the Roslin Institute established the technology to create transgenic chickens that produce large quantities of a target protein in their egg-white. This platform has now been commercialised through Roslin Technologies.
Porcine CSF1-Fc, Human CSF1-Fc, Canine CSF1-Fc, Human interferon α 2α and Trastuzumab are all available for purchase.
A portfolio of monoclonal antibodies has been developed by the Roslin Institute as part of the “Immunological Toolbox” project. Roslin Technologies has agreed an exclusive licence to sell this portfolio of antibodies. Conjugated anti-porcine ADGRE-1, anti-chicken CSF1 and anti-porcine CSF1 are available for use in ELISA, flow cytometry and immunohistochemistry studies.
PGC Expression System & Reagents
Our vision is to develop an in vitro expression system via genetic manipulation of chicken primordial germ cells (PGCs). This will provide an intermediate step to identify targets for production of transgenic chickens or to produce smaller quantities of proteins that retain the benefits of chicken-associated post-translational modifications.