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Case study

iPS cell lines: From Concept to commercialisation

At Roslin Technologies, we focus on the science of sustainable protein.

Our main aim is to develop ethical protein alternatives to traditionally produced meat. We do this using our novel stem cell platform to produce induced pluripotent stem (iPS) cell lines for various species.

Case study

iPS cell lines:
From Concept to commercialisation

At Roslin Technologies, we focus on the science of sustainable protein.

Our main aim is to develop ethical protein alternatives to traditionally produced meat. We do this using our novel stem cell platform to produce induced pluripotent stem (iPS) cell lines for various species.

Two piglets facing the camera
Porcine iPS cells differentiated into Adipocytes

From humans to animals

Our stem cell unit, Animal Cells, was established in 2018 with Dr Joe Mee spearheading the work. We combined our focus on sustainable protein and expertise in animal cell culture to investigate the effects of genome editing on specific cellular targets. We started by creating novel genomic editing technologies, however soon realised the potential application of iPS cell lines for creating cultivated meat products.

While iPS cell lines are not a new concept for human research, very little has been translated across into animal research, especially for larger animals that are important livestock species. Our cell lines are bespoke to livestock animals, often from recalcitrant species.

Unique offering

Roslin Tech’s iPS cell lines are a unique offering. They offer the ability to produce sustainable, slaughter-free, antibiotic-free, environmentally friendly, high quality nutritious cultivated meat products.

They are immortal lines, with no need for repeat sampling from animals. Not only does this improve animal welfare and allow for harm-free growth, but it also ensures that the quality of the cell lines does not need to be repeatedly assessed and evaluated. Throughout the growth cycle, cells are produced in a harm-free environment. We have produced serum-free growth media, to ensure that the production process does not involve the use of materials that are derived directly from animals.

Porcine Chondrocytes differentiated from iPS cell lines
Porcine Bone derived from iPS cell lines

Lines in development

Once our iPS cell lines are generated, the expertise of our team enables them to confirm differentiation into cells of interest (such as fat and muscle). We also ensure the cell lines’ longevity and durability to withstand multiple passages – key attributes for their use in cultivated meat products.

With porcine lines already available for use in commercial product development, our cell lines are now under licence with multiple commercial customers. We are working on further species lines for release later in 2021 – find out more about our iPS cell lines and their uses on our dedicated page for Cultivated Meat.

Find out more about our iPS cell lines on our dedicated pages

Read more

Piglets

SCALING UP IPS CELL LINES FOR CULTIVATED MEAT PRODUCTION

Cultivated meat has the ability to revolutionise the food industry, however scale up poses a new challenge. Roslin Technologies is partnering with the University of Edinburgh to find new ways to sustainably scale our iPS cell lines.

Piglets

Vaccine Delivery Vehicle: Parasite Engineering

As part of Roslin Tech’s drive to enhance sustainable protein production, we partner with academics conducting cutting-edge research that can have commercial impacts on the livestock industry.

Piglets

Gene Editing Shrimp: White Spot Syndrome Virus

As part of our drive for sustainable protein production, Roslin Technologies partner with academics working in key Scottish industries such as aquaculture.

Piglets

Genetic breeding programme for pigs

Danish Genetics represent Denmark’s leading pig breeders, producers and vendors who are working to provide a sustainable, welfare focussed system.

From humans to animals

Our stem cell unit, Animal Cells, was established in 2018 with Dr Joe Mee spearheading the work. We combined our focus on sustainable protein and expertise in animal cell culture to investigate the effects of genome editing on specific cellular targets. We started by creating novel genomic editing technologies, however soon realised the potential application of iPS cell lines for creating cultivated meat products.

While iPS cell lines are not a new concept for human research, very little has been translated across into animal research, especially for larger animals that are important livestock species. Our cell lines are bespoke to livestock animals, often from recalcitrant species.

Porcine iPS cells differentiated into Adipocytes

Unique offering

Roslin Tech’s iPS cell lines are a unique offering. They offer the ability to produce sustainable, slaughter-free, antibiotic-free, environmentally friendly, high quality nutritious cultivated meat products.

They are immortal lines, with no need for repeat sampling from animals. Not only does this improve animal welfare and allow for harm-free growth, but it also ensures that the quality of the cell lines does not need to be repeatedly assessed and evaluated. Throughout the growth cycle, cells are produced in a harm-free environment. We have produced serum-free growth media, to ensure that the production process does not involve the use of materials that are derived directly from animals.

Porcine iPS cells differentiated into Adipocytes

Lines in development

Once our iPS cell lines are generated, the expertise of our team enables them to confirm differentiation into cells of interest (such as fat and muscle). We also ensure the cell lines’ longevity and durability to withstand multiple passages – key attributes for their use in cultivated meat products.

With porcine lines already available for use in commercial product development, our cell lines are now under licence with multiple commercial customers. We are working on further species lines for release later in 2021 – find out more about our iPS cell lines and their uses on our dedicated page for Cultivated Meat.

Porcine Bone derived from iPS cell lines

Find out more about our iPS cell lines on our dedicated pages

Read more

Piglets

SCALING UP IPS CELL LINES FOR CULTIVATED MEAT PRODUCTION

Cultivated meat has the ability to revolutionise the food industry, however scale up poses a new challenge. Roslin Technologies is partnering with the University of Edinburgh to find new ways to sustainably scale our iPS cell lines.

Piglets

Vaccine Delivery Vehicle: Parasite Engineering

As part of Roslin Tech’s drive to enhance sustainable protein production, we partner with academics conducting cutting-edge research that can have commercial impacts on the livestock industry.

Piglets

Gene Editing Shrimp: White Spot Syndrome Virus

As part of our drive for sustainable protein production, Roslin Technologies partner with academics working in key Scottish industries such as aquaculture.

Piglets

Genetic breeding programme for pigs

Danish Genetics represent Denmark’s leading pig breeders, producers and vendors who are working to provide a sustainable, welfare focussed system.